Course Overview
Personalized medicine has moved out of the research lab and into the exam room. Consumer and clinician-ordered SNP panels (3X4 Genetics, Nutrition Genome, DNAlife, StrateGene) and DNA-methylation biological-age tests (TruDiagnostic TruAge, DunedinPACE, GrimAge, PhenoAge) are now common inputs to longevity and performance programs. TWI 211 is an intermediate-level clinical course that teaches DPTs, DCs, and allied movement-medicine professionals how to read these reports competently, translate individual variants and epigenetic scores into evidence-graded lifestyle recommendations, and integrate the results into a written care plan without overstepping scope of practice.
Curriculum
1
Genomics 101: DNA, SNPs, and gene expression
2
Consumer SNP panels: 3X4, Nutrition Genome, DNAlife, StrateGene
3
Key clinical SNPs: MTHFR, COMT, APOE, VDR, GST, FTO, TCF7L2, ACE/ACTN3
4
DNA-methylation clocks I: Horvath, PhenoAge, GrimAge
5
DNA-methylation clocks II: DunedinPACE, TruDiagnostic TruAge, OMICmAge
6
Pharmacogenomics primer: CPIC, PharmGKB, and CYP2D6/2C19/2C9
7
Nutrigenomics and exercise-genomics: from SNP to plan
8
Integrating genomic and epigenetic data into individualized plans
9
Ethics, GINA, HIPAA, and scope of practice
10
Building a genomic/epigenetic service line: workflow, pricing, referrals